Immunosuppression led to the development of autoimmunity in lab mice

These researchers found that injecting type 1 diabetes-prone mice with dead myobacteria (or BCG vaccine) could protect them against type 1 diabetes. However, they found that disease could be induced in disease can be induced in the protected mice by chemo treatment with cyclophosphamide to suppress the immune system.

I thought that this might be interesting because other immunosuppresants -corticosteroids, Cellcept, Imuran, and rituximab- are some drugs being tried by long haulers. I worry about the long-term side effects of these drugs as they may lead to autoimmune disease and cancer.