Black seed oil comes from the Nigella Sativa plant’s seeds. Long haulers should definitely consider trying this because it is pretty safe (sold in some supermarkets), works for some people, and doesn’t cost much.
A similar intervention, Nigella Sativa seeds (not the oil but the seed), is currently a first-line therapy in the FLCCC protocol for vaccine injury.
How it works is unclear at the moment.
- Thymoquinone in black seed oil binds to the S1 spike protein, perhaps causing the body to react less to it.
- Thymoquinone, carvacrol, and other chemicals in the oil have antimicrobial properties. Carvacrol is effective against microbial biofilms and works better against them than many prescription antibiotics. See the wiki page on multiple persistent infections for links to scientific studies (e.g. papers from Zhang’s lab).
39% saw an improvement.
7.0% reported negative effects. 1 person vomited and answered “symptoms stayed the same” so their response did not show up as slight worsening.
The second React19 survey (on persistent symptoms) asked participants which drugs helped them. 2.4% said that black seed oil (either seed or oil) was one of the drugs that helped them.
The Maju brand’s packaging recommends 4 teaspoons a day, which is roughly 20mL a day. Another brand (Amazing Herbs) suggests starting with a half-teaspoon a day until the taste improves.
The FLCCC protocol calls for 0.2-0.5 grams of seed twice a day, which could add up to 1g/day. One teaspoon/day of the oil (which is likely more potent than the seed) is roughly 5g/day.
There isn’t good information right now regarding dosing. In theory, higher doses may be needed to fight biofilm infections from bacteria and fungi.
It is sometimes sold in ethnic supermarkets for Iranians, Pakistanis, and Indians.
Some online retailers such as iHerb sell a larger supermarket-sized bottle. If your plan is to consume 20mL/day, then a 250mL bottle will last 12 and a half days. Pure Indian Foods, Organic Cold Pressed Virgin Black Seed Oil, 250 ml
It should be noted that thymoquinone (the active ingredient of Nigella Sativa) decreases the absorption of cyclosporine and phenytoin. Patients taking these drugs should, therefore, avoid taking Nigella Sativa. Furthermore, two cases of serotonin syndrome have been reported in patients taking Nigella Sativa who underwent general anaesthesia (probable interaction with opiates).
You can skim through the 1-star reviews on Amazon, iHerb, etc. to see what can go wrong. (The 5-star reviews often say that black seed oil cures everything.)